Curriculum Vitae - Robert C. Getts Ph.D.

Education:

Lehigh University, Bethlehem, PA
Ph.D. in Chemistry (Biochemistry), 10/91
GPA: 3.9 of 4.0

University of Scranton, Scranton, PA
M.A. in Biochemistry, 8/87
GPA: 3.95 of 4.0

University of Scranton, Scranton, PA
B.S. in Biochemistry, 5/86
GPA: 3.9 of 4.0

Research Experience:

4/94 to present: Senior Research Scientist, Polyprobe Inc., Philadelphia, PA 1913 1, Research and Development on DNA Dendrimers for Use in Nucleic Acid Detection Assays.

4/94 to present: Collaboration, The Lankenau Medical Research Center, Wynnewood, PA 19096, Characterization of Proteins Associated with a DNA End-Binding Complex.

7/91 to 4/94: Postdoctoral Research Associate, The Lankenau Medical Research Center, Wynnewood, PA 19096, The Purification of a Double Stranded DNA End-Binding and Repair Complex.

1/88 to 7/91: Ph.D. Thesis, The Positional Dependence of Oligopurine Tracts in Nucleosomes.

7/86 to 7/87: Masters Thesis, The Effects of Vitamin A and Vitamin E on the Lipids of the Erythrocyte Membrane.

5/86: Undergraduate Thesis, The Effects of Vitamin A and Vitamin E Deficiencies on Erythrocyte Fragility.

Technical Skills:

Grant Writing, Tissue Culture, Molecular Cloning, DNA Sequencing, PCR, Northern, Southern, and DOT Blot Analysis, FISH, Native PAGE, SDS PAGE, Protein Purification, Western (and South-western) Blot Analysis, Enzyme Kinetics, FPLC, BPLC, GC, Gel Filtration and Ion-exchange Chromatography (20 liter Column), Gradient Ultra-centrifugation, Fluorescent and UV/VIS Spectroscopy.

Honors/Activities:

Vice President of Local Unit of the American Cancer Society, Member of the American Association of Clinical Chemists (AACC), and the American Association for the Advancement of Science (AAAS).

References: Available upon request.

Publications:

Reviewed Journal Articles:

Getts, R. C. and Behe, M. J., Eukaryotic DNA Does Not Form Nucleosomes as Readily as Some Prokaryotic DNA. Nucleic Acids Research, 19(21), 1991, 5923-5927.

Getts, R. C. and Behe, M. J., Isolated Oligopurine Tracts Do Not Significantly Affect the Binding of DNA to Nucleosomes., Biochemistry, 31, 1992, 380-385.

Getts, R. C. and Stamato, T. D., Absence of a Ku-like DNA End-Binding Activity in the xrs Double-strand DNA Repair-deficient Mutant., Journal of Biological Chemistry, 269(23), 1994, 15981-15984.

Abstracts:

Nilsen T. W., Getts, R. C., Tian, N, and Grayzel, J., Dendritic DNA: Covalent Hyperbranched Superstructures., Abstract Presented at AACC Meeting, San Diego, 1994.

Nilsen T. W., Vogelbacker, H. V., Getts, R. C., Tian, N, and Grayzel, J., Dendrimer Signal Enhancement in Blot Assays., Abstract Presented at AACC Meeting, Chicago, 1996.

Mauldin, S. K. Getts, R. C. and Stamato, T. D., Purification of a DNA End-binding Complex with a non-Ku-like Mobility Shift Pattern., Abstract Presented at Radiation Research Meeting, Chicago, 1996.

Submitted Journal Articles:

Motyka, L., Getts, R.C. Guerriero, S. and Stamato, T.D., Analysis of Repair of Restriction Enzyme-Induced DNA Damage in CHO Cells and the Double Strand Repair Mutant, XR- 1. Submitted 1996

Journal Articles in Preparation:

Mauldin, S. K., Getts, R.C., and Stamato, T. D., The Association of a Known Nuclear Scaffold Protein with the Ku DNA End-Binding Repair Complex., In preparation 1997

Getts, R, C. and Stamato T. D., Purification of a DNA Binding Protein Which Enhances DNA Double Strand Ligation., In preparation 1997

Getts, R. C. Guerriero, S., and Stamato, T. D., Inhibition of DNA Double Strand Break Repair with a DNA Hairpin Molecule., In preparation 1997